Year : 2016

Volume : Volume 6

Issue : Issue 1s

Address for correspondence :
Dr. Anshuman Gautam
a.gautam113@gmail.com

Abstract

Background:  Periodontitis is one of the most common oral diseases and is characterized by gingival inflammation and alveolar bone resorption. It is caused by host immune responses to periodontal microorganisms. The field of “perioceutics”, or the use of pharmacological agents specifically developed to better manage periodontitis, is emerging to aid in the management of susceptible patients who develop periodontal disease. Host modulatory therapy, which can be used to bring down excessive levels of enzymes, cytokines, and prostanoids as well as modulate osteoclast function, is the key to addressing many of these risk factors that have adverse effects on the host response. Although, innumerable therapies are beginning to surface, a handful of these have true potential in clinical practice.

Keywords: periodontitis, host modulation, cytokines, inhibition, HMT.