Original Article

Year : 2023

Volume : Volume 14

Issue : Issue 3

Tetracycline HCl-Loaded Fibers as Adjunct to Scaling and Root Planing

Dr. Nishi Dave

Address for correspondence :
Dr. Nishi Dave
Nishid2301@gmail.com

Abstract


Background and Aim: Periodontal diseases are considered as infections of periodontium with a bacterial etiology, an immune response, and 
subsequent tissue destruction. Local delivery of antimicrobial agents in periodontitis entails antimicrobial therapy placed directly in periodontal 
pockets. Local drug delivery into the periodontal pocket is an effective treatment associated with mechanical debridement. The main goal of 
local drug delivery is to decrease periodontal pocket depth. Objective is to treat periodontal pocket using tetracycline fibers as well as comparing 
the results post-SRP (control group). Material and Methods: Thirty subjects (60 sites) were selected and were distributed randomly into Site 
A (SRP) and Site B (SRP + tetracycline fiber) based on inclusion and exclusion criteria. Statistical Tests: The relative efficacy of the two 
treatment modalities was evaluated using the paired Student’s t-test, and the comparative evaluation between the two groups was done using 
repeated measure ANOVA. Results: Mean periodontal pocket score was less in test group (2.40 ± 0.49) than control group (2.83 ± 0.59) 
at 3 month time period. Statistically, significant difference was present in periodontal pocket score between test group and control group at 
3 month time period. Conclusion: From the study, it can be concluded that tetracycline filled type I collagen fiber (Periodontal Plus AB) 
therapy enhances the benefits of scaling and root planing rather than SRP alone