Year : 2020

Volume : Volume 11

Issue : Issue 3

Address for correspondence :
Dr. B.V. Harish.
bvharish@gmail.com

Abstract

Background:  Plasmacytoma found as a mixed radiopaque radiolucent lesion around an impacted molar is uncommon, however it is essential to rule out for its counterpart i.e., multiple myeloma. Solitary bone plasmacytoma, typified by clonal proliferation of plasma cells, belongs to a group of lymphoproliferative clinical disorders. It most typically involves a single bone or extramedullary site. It is a dyscrasia of plasma cells that involves the jaw bones very rarely, and which is commonly seen in the retromolar area, angle, and ramus of the mandible. They must be differentiated from multiple myeloma as prognosis between both vary considerably. It accounts for 3% of all plasma cell neoplasms, with approximately 50% of the cases transforming into MM over 34 years. This report describes a case of a mixed radiopaque-radiolucent lesion in the mandible, later diagnosed as plasmacytoma in an old-aged male patient, treated surgically, and systemic workup was done to rule out multiple myeloma. Despite the rarity of plasmacytoma in the jaws, there is an incidence of 0.15% of cases of multiple myeloma, the first manifestation of the disease appears in the jawbones and oral cavity.

Keywords: Solitary plasmacytoma, plasma cells, multiple myeloma.