Year : 2021

Volume : Volume 12

Issue : Issue 4

Address for correspondence :
Priyanka S. Padalkar
priyapadalkar08@gmail.com

Abstract

Background: Periostin is a matricellular protein highly expressed in periosteum, periodontal ligament and is essential for tissue integrity and maturation. It plays a role in collagen fibrillogenesis and is downregulated in periodontal disease. The goal of periodontal regenerative therapy is to predictably restore the tooth’s supporting periodontal tissues and form a new connective tissue attachment of periodontal ligament (PDL) f ibers and new alveolar bone. Periostin might play a pivotal part in regeneration of the PDL and alveolar bone following periodontal surgery. Recently, several studies have suggested that periostin may be an important regulator of periodontal tissue formation by promoting collagen f ibrillogenesis and the migration of fibroblasts and osteoblasts. The aim of this article is to provide an extensive review of the implications of periostin in periodontal tissue biology and its potential use in periodontal tissue regeneration.

Keywords: Periostin, Periodontal ligament, Periodontal tissues.