Year : 2023

Volume : Volume 14

Issue : Issue 2

Address for correspondence :
Dr. Saloni Mistry
salonimistry@ymail.com

Abstract

Hydrogels (HG) are a promising biomaterial for the therapeutic administration of cells and bioactive compounds for tissue regeneration and
drug delivery in dentistry and medicine. These hydrophilic polymers can typically be divided into two groups: Natural polymers derived
from tissues or other sources of natural materials, and synthetic polymers produced by combining principles from organic chemistry and
molecular engineering. Avariety of organic and synthetic biomaterials, such as chitosan, collagen or gelatin, alginate, hyaluronic acid, heparin,
chondroitin sulfate, polyethylene glycol, and polyvinyl alcohol, are used for its synthesis. For prolonged protein release, targeted drug delivery,
and tissue engineering, HGs have become efficient because of their high biocompatibility and microporous structure with adjustable porosity
in periodontal regeneration. This review aims to summarize the most commonly used HG in tissue engineering, emphasizing those that are
studied for the regeneration of oral tissues, their biological effects, and their clinical implications in prosthodontics.