Year : 2018

Volume : Volume 8

Issue : Issue 2

Address for correspondence :
Dr. Supriya Singh.
SupriyaSingh@gmail.com

Abstract

Background:  Tobacco smoking have been attributed to as major risk factor for carcinogenesis. The oral mucosa of smokers exhibits many changes. Exfoliative cytological methods have been employed to examine these changes, especially in cells collected from the buccal mucosa. Atypical cells are present on surface of mucosa in smokers compared to person who doesn’t have any deleterious habit. Oral exfoliative cytology is popular as an oral cancer screening tool, as it is a painless, non-invasive procedure, and is well accepted by patients as it causes little discomfort. Materials and Method: The aim of this study was to compare the cytology of cells collected from apparently normal buccal mucosa in tobacco smokers, with results obtained for nonsmokers.  Objective was to evaluate presence of atypical cells in apparently normal mucosa among smokers using Cytomorphometry.  The study population comprised of study group and control group. Result: Results were obtained by measuring nuclear diameter, cytoplasmic diameter, nuclear and cytoplasmic ratio in each sub group and comparing between study and control group. There was statistically significant difference between study group and control group. Conclusion-The effect of smoking from this study convince evidenced that tobacco have definitively deleterious effect on oral mucosa in terms of nuclear cytoplasmic changes, which are the key features for early diagnosis of malignancy.

Keywords: Smoking, Oral exfoliative cytology, Nuclear-cytoplasmic ratio, Cytomorphometry.