Year : 2019

Volume : Volume 10

Issue : Issue 3

Address for correspondence :
Dr. Richa Kumari.
khannashilpa03@gmail.com

Abstract

Aim:  To evaluate the efficacy of tranexamic acid on the intraoperative blood loss in third molar surgery.  Materials and Methods: A split-mouth comparative study was conducted comprising of 30 healthy patients between September 2018 and February 2020 who were diagnosed clinically and radiographically with identical bilateral impacted lower third molars necessitating surgical removal. The right side of the patient was designated as the test side where tranexamic acid was administered to the patient prior to the surgical removal of the impacted third molar, and the left side of the patient was designated as control side where the surgical removal of impacted third molar was performed conventionally. All surgical interventions for the removal of impacted third molars were performed using a modified Ward’s incision. Patients were evaluated for intraoperative blood loss, duration of the procedure, VAS score for pain, hemodynamic changes and adverse effects if any.  Results: The results of this study reveal that there is a significant reduction in the amount of intraoperative blood loss with much better and clear surgical field visibility in the test side when compared to the control side. This also resulted in reduced duration of the procedure on the test side when compared to the control side. The hemodynamic status of the patients was stable in the perioperative phase with no major complications were noted with the use of tranexamic acid Conclusion: The results of this study show that Tranexamic acid is definitely a safe and effective drug that can be employed to reduce the intraoperative blood loss in addition to enhancing the visibility of the surgical field, thereby permitting the surgical intervention to be performed with ease.

Keywords: Tranexamic Acid, blood loss, third molar surgery.