Year : 2017

Volume : Volume 7

Issue : Issue 1

Address for correspondence :
Dr. Joy R Das
drjoy303@gmail.com

Abstract

Background:  The use of autologous platelet concentrates mainly platelet rich plasma has been of relevance recently in the field of Oral and Maxillofacial surgery. These concentrates had the ability to improve the hard and soft tissue healing. This ability of the platelet concentrates had been studied in the healing after mandibular third molar impaction surgery. The various parameters like bone density  and post operative pain, were taken into account. The patients were evaluated on 1st,2nd.7th  day, first month and second month post operatively. The values for each parameters were found out and tabulated. Platelet-rich fibrin (PRF) is a fibrin meshwork, in which platelet cytokines, growth factors, and cells are entrapped and discharged after a period and can serve as a resorbable film. PRF is the next generation of platelet concentrates equipped to improve arrangement without biochemical blood handling. Materials and methods: Twelve patients, seven males and five females with bilaterally impacted mandibular third molars were included in the study. Autologous platelets were concentrated. This was applied on one of the sockets which was randomly taken as the test side. The other socket was treated as the control. Results: Statistical analysis was done using Mann Whitney U test for pain which revealed the values for pain being statistically significant for the test side. Bone density was analysed with T-test . Bone density values were statistically significant for the test side. Summary and conclusion: platelet rich plasma is a surgical additive that can be used to improve bone and soft tissue healing. It contains a wide array of growth factors that are responsible for their healing potential.

Keywords: Platelet concentrates, growth factors, bone density, gray value scale, pain, platelet rich fibrin.