Year : 2024

Volume : Volume 15

Issue : Issue 1

Address for correspondence :
Dr. Indrasri Das
indrasridasdoc87@gmail.com

Abstract

Pemphigus vulgaris (PV) is a rare autoimmune blistering disease that frequently affects the oral mucosa and is characterized by painful mucocutaneous blisters and erosions. In this particular case report, a 26-year-old woman reported desquamative gingivitis and gingival overgrowth, underscoring the difficulty in detecting and treating oral disorders that could have systemic effects. Given the patient’s history of phenytoin use, drug-induced gingival enlargement, which resembled PV was suspected. Clinical, histopathological, and immunological evidence were used to make the diagnosis, and ELISA testing confirmed the existence of autoantibodies against Desmoglein 3. Immunosuppressive medications, such as corticosteroids and immunosuppressive drugs, were commonly used in the treatment, while newer options like Rituximab presented hopeful alternative with less adverse effects. This example highlights how PV management is changing, with targeted medicines being investigated more and more to enhance patient’s outcome and quality of life, underscoring the significance of a comprehensive approach to diagnosis and treatment.