Year : 2018

Volume : Volume 9

Issue : Issue 1

Address for correspondence :
Dr. Mohit Bansal.
MohitBansal@gmail.com

Abstract

Aim:  This study was aimed to assess and compare antimicrobial effect of 2% chlorhexidine (CHX) and NAcetylcysteine (NAC) irrigating solutions against two different bacterium species.  Materials & Methods: This study was performed on 60 freshly extracted non-carious permanent maxillary incisors teeth of both genders. Biomechanical preparation was completed up to size 40 K- file. Well prepared microbial suspensions of mixed culture of the studied bacterium were inserted into root canals. It was further incubated for 48 hours. All 60 samples were segregated into 3 groups. Group I (Chlorhexidine), group II (NAcetylcysteine NAC). The third group was kept as control group (sterile distilled water). The antimicrobial effect in each group was observed, documented and compared.  Results: Statistical analysis was completed using statistical software Statistical Package for the Social Sciences version 20. S. Mutans bacterial colony count was highest in group III and lowest in group II. Specifically, it was 5.22±0.56 in group I, 2.42±0.46 in group II, 10.21± 2.32 in group III. The difference was significant (P< 0.05).  Conclusion: N-Acetylcysteine showed to be extremely efficient against colonies of E. faecalis and S. mutans. Hence N-Acetylcysteine can be used as an alternative root canal irrigant. Here in this study the authors have studied effectiveness of two irrigating solutions wherein N-Acetylcysteine found to be more effective in lowering bacterial count. N-Acetylcysteine may possibly be proved as promising innovation in endodontic advancements and technologies.

Keywords: Chlorhexidine, Irrigating solution, Streptococcus Mutans.