Year : 2023

Volume : Volume 14

Issue : Issue 1

Address for correspondence :
Meenakshi Boddun
boddunmeenakshi@gmail.com

Abstract

 Introduction: C-reactive protein (CRP) is an acute phase protein and sensitive systemic marker which rises in response to inflammation. Studies 
indicate that CRP levels are raised in periodontal diseases. Aim: To determine the association of CRP with periodontal disease. Objective: 
To measure serum level of CRP in healthy individuals and subjects with gingivitis, healthy individuals and subjects with periodontitis, and 
in subjects with gingivitis and periodontitis. Method and Material: The present study was under taken to determine the serum CRP levels 
in normal healthy individuals which ranges from 3mg/l to 5 mg/l, in patients having gingivitis and patients having periodontitis without any 
inflammatory or immunological conditions or diseases. A total of 45 Systemically healthy subjects were selected for the study, subjects were 
divided into groups A, B and C, with group A having healthy controls, group B with gingivitis, and group C having periodontitis patients. the 
serum samples were collected and analyzed using slide agglutination technique and immunoturbidity method in the laboratory. Result: The 
result showed significantly raised level of serum CRP in individuals with periodontitis. It was concluded that periodontitis acts as a factor 
to add to the inflammatory burden of the individual and may result in increased risk of atherosclerosis based on serum CRP concentrations. 
Conclusion: The results of the present study shows that periodontitis is suggestively associated with increased systemic CRP levels.
 Keywords: C-reactive, Gingivitis, Inflammatory marker, Periodontal disease.