Journal of Research and Advancement in Dentistry
Official publication of Magadh University and Kolhan University, Government of Bihar and Jharkhand, India
Official publication of Magadh University and Kolhan University, Government of Bihar and Jharkhand, India
Year : 2019
Volume : Volume 10
Issue : Issue 3
Address for correspondence :
Dr. Naina Pattnaik.
nainapattnaik@gmail.com
Background: Donohue syndrome (also referred to as Leprechaunism) is an extremely rare and severe genetic disorder. The individuals thus affected are associated with extreme insulin resistance. Most of the diseases present in Donohue syndrome is considered to be due to the insulin receptor binding the insulin like growth factor, regulating the growth of the embryo and the regulation of blood sugar. A case of 13-year-old female having Donohue syndrome is briefly described in this article.
Keywords: Donohue syndrome, Insulin receptor, Growth factor, Genetic disorder, Orofacial features.
