Year : 2020

Volume : Volume 11

Issue : Issue 1

Address for correspondence :
Dr. Rina Girish Mehta.
reemehta46@gmail.com

Abstract

Tremendous progress in study of hormones’ functions has raised the knowledge about their relationship between normal physiology and disease conditions of the living body. Human cells sensitive to viruses are   susceptible to cause an infection. Disease severity is reflected by the number and the nature of cells infected, viral reproduction, inflammation and an immune response of an individuals. Hormones may alter a course of viral infection may be beneficial or detrimental to the host is a study scope as a natural or an experimental challenge for researchers. Hormonal balance is effective to prevent viral infection. Shaping of an immunity is depends on the kinetics of host immune response to virus (initial phase) and an extent of virus induced pathology (T-cell mediated lethality) by the role of HPA (Hypothalamus-Pituitary-Adrenal) Axis, cytokines and glucocorticoids.   Hormonal administration after   viral infection does not prove to protect the host from disease condition, only supportive to reduce progress and severity of disease status. Efforts by this review is to focus on prevention as a priority rather than curative measures against viruses for human existence.

Keywords: Hormones, Viruses, HPA Axis, Glucocorticoids, Immune –regulating signals.